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Assay Detail

CHEMBL978899

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against human G361 cells by MTT assay
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type G-361
Confidence 1 — Organism
Curated By Autocuration

Target

G-361 (CHEMBL614036)
Type CELL-LINE
Organism Homo sapiens

Publication

Synthesis of potent antitumor and antiviral benzofuran derivatives.
Galal SA, Abd El-All AS, Abdallah MM, El-Diwani HI.
Bioorg Med Chem Lett (2009) 19 : 2420 -2428
PubMed 19345581 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 10 10.51 10.58

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL468539 1 10.58
CHEMBL466907 1 10.58
CHEMBL449897 1 10.58
CHEMBL466114 1 10.54
CHEMBL466909 1 10.53
CHEMBL3143911 1 10.52
CHEMBL468747 1 10.50
CHEMBL513819 1 10.50
CHEMBL511905 1 10.42
CHEMBL466908 1 10.32

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL468539 IC50 = 0.0263 nM 10.58
CHEMBL466907 IC50 = 0.0263 nM 10.58
CHEMBL449897 IC50 = 0.0263 nM 10.58
CHEMBL466114 IC50 = 0.0287 nM 10.54
CHEMBL466909 IC50 = 0.0298 nM 10.53
CHEMBL3143911 IC50 = 0.0305 nM 10.52
CHEMBL468747 IC50 = 0.0316 nM 10.50
CHEMBL513819 IC50 = 0.0313 nM 10.50
CHEMBL511905 IC50 = 0.0384 nM 10.42
CHEMBL466908 IC50 = 0.0481 nM 10.32