Assay Detail
Functional
CHEMBL979313
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Cytotoxicity against human SKOV3 cells after 48 hrs by SRB assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | SK-OV-3 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Cytotoxic xanthones from Cudrania tricuspidata.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.43 | 5.87 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL428647 | PACLITAXEL | 4.0 | 1 | 5.87 |
| CHEMBL370126 | MACLURAXANTHONE B | — | 1 | 5.37 |
| CHEMBL197916 | CUDRAXANTHONE L | — | 1 | 5.33 |
| CHEMBL200640 | CUDRATRICUSXANTHONE A | — | 1 | 5.15 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL428647 | PACLITAXEL | IC50 | = | 1350.0 | nM | 5.87 |
| CHEMBL370126 | MACLURAXANTHONE B | IC50 | = | 4240.0 | nM | 5.37 |
| CHEMBL197916 | CUDRAXANTHONE L | IC50 | = | 4720.0 | nM | 5.33 |
| CHEMBL200640 | CUDRATRICUSXANTHONE A | IC50 | = | 7090.0 | nM | 5.15 |