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Assay Detail

CHEMBL980033

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of HIV1 3B reverse transcriptase activity
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Human immunodeficiency virus 1
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Human immunodeficiency virus type 1 reverse transcriptase (CHEMBL247)
Type SINGLE PROTEIN
Organism Human immunodeficiency virus 1

Publication

Anti-HIV-1 activity of phloroglucinol derivative, 6,6'-bieckol, from Ecklonia cava.
Artan M, Li Y, Karadeniz F, Lee SH, Kim MM, Kim SK.
Bioorg Med Chem (2008) 16 : 7921 -7926
PubMed 18693022 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 2 6.13 6.29

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL443626 1 6.29
CHEMBL502202 1 5.97

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL443626 EC50 = 510.0 nM 6.29
CHEMBL502202 EC50 = 1070.0 nM 5.97