Assay Detail
Functional
CHEMBL980501
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Antiplasmodial activity against chloroquine-sensitive Plasmodium falciparum Ghana by LDH reporter assay
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium falciparum |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Antiparasitic activity of some xanthones and biflavonoids from the root bark of Garcinia livingstonei.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 4.70 | 5.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL500482 | — | — | 1 | 5.22 |
| CHEMBL454538 | GARCILIVIN A | — | 1 | 5.17 |
| CHEMBL188061 | — | — | 1 | 5.00 |
| CHEMBL463023 | VOLKENSIFLAVONE | — | 1 | 4.32 |
| CHEMBL479289 | — | — | 1 | 4.28 |
| CHEMBL482023 | — | — | 1 | 4.23 |
| CHEMBL499445 | GARCIVILIN C | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL500482 | — | IC50 | = | 6000.0 | nM | 5.22 |
| CHEMBL454538 | GARCILIVIN A | IC50 | = | 6700.0 | nM | 5.17 |
| CHEMBL188061 | — | IC50 | = | 10000.0 | nM | 5.00 |
| CHEMBL463023 | VOLKENSIFLAVONE | IC50 | = | 48000.0 | nM | 4.32 |
| CHEMBL479289 | — | IC50 | = | 52000.0 | nM | 4.28 |
| CHEMBL482023 | — | IC50 | = | 59000.0 | nM | 4.23 |
| CHEMBL499445 | GARCIVILIN C | IC50 | > | 64000.0 | nM | - |