Assay Detail
Binding
CHEMBL980535
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Inhibition of human recombinant CDK5/p25
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Butyrolactone I derivatives from Aspergillus terreus carrying an unusual sulfate moiety.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 6.51 | 7.11 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1242973 | BUTYROLACTONE I | — | 1 | 7.11 |
| CHEMBL14762 | SELICICLIB | 2.0 | 1 | 6.80 |
| CHEMBL460464 | — | — | 1 | 5.62 |
| CHEMBL465047 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1242973 | BUTYROLACTONE I | IC50 | = | 77.0 | nM | 7.11 |
| CHEMBL14762 | SELICICLIB | IC50 | = | 160.0 | nM | 6.80 |
| CHEMBL460464 | — | IC50 | = | 2400.0 | nM | 5.62 |
| CHEMBL465047 | — | IC50 | > | 100000.0 | nM | - |