Assay Detail
Binding
CHEMBL980943
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Inhibition of human liver cathepsin B
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Synthesis and calpain inhibitory activity of peptidomimetic compounds with constrained amino acids at the P2 position.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 6.14 | 6.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL304784 | — | — | 1 | 6.82 |
| CHEMBL470973 | — | — | 1 | 6.06 |
| CHEMBL513049 | — | — | 1 | 5.54 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL304784 | — | Ki | = | 150.0 | nM | 6.82 |
| CHEMBL470973 | — | Ki | = | 880.0 | nM | 6.06 |
| CHEMBL513049 | — | Ki | = | 2910.0 | nM | 5.54 |