Assay Detail
Binding
CHEMBL981109
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of NK1 receptor
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Intermediate |
Publication
The many roles for fluorine in medicinal chemistry.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 10.08 | 10.15 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL140745 | — | — | 1 | 10.15 |
| CHEMBL52330 | — | — | 1 | 10.05 |
| CHEMBL1471 | APREPITANT | 4.0 | 1 | 10.05 |
| CHEMBL142819 | — | — | 1 | 10.05 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL140745 | — | IC50 | = | 0.07 | nM | 10.15 |
| CHEMBL52330 | — | IC50 | = | 0.09 | nM | 10.05 |
| CHEMBL1471 | APREPITANT | IC50 | = | 0.09 | nM | 10.05 |
| CHEMBL142819 | — | IC50 | = | 0.09 | nM | 10.05 |