Assay Detail
Binding
CHEMBL981115
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]CP-55940 from human CB1 receptor expressed in CHO cells
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | CHO |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
The many roles for fluorine in medicinal chemistry.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 9.01 | 9.54 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL220360 | TARANABANT | 3.0 | 1 | 9.54 |
| CHEMBL373626 | — | — | 1 | 9.27 |
| CHEMBL219480 | — | — | 1 | 8.83 |
| CHEMBL374791 | — | — | 1 | 8.74 |
| CHEMBL217862 | — | — | 1 | 8.69 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL220360 | TARANABANT | IC50 | = | 0.29 | nM | 9.54 |
| CHEMBL373626 | — | IC50 | = | 0.54 | nM | 9.27 |
| CHEMBL219480 | — | IC50 | = | 1.47 | nM | 8.83 |
| CHEMBL374791 | — | IC50 | = | 1.8 | nM | 8.74 |
| CHEMBL217862 | — | IC50 | = | 2.03 | nM | 8.69 |