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Assay Detail

CHEMBL981116

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of prostaglandin DP receptor
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Intermediate

Target

Prostaglandin D2 receptor (CHEMBL4427)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

The many roles for fluorine in medicinal chemistry.
Hagmann WK.
J Med Chem (2008) 51 : 4359 -4369
PubMed 18570365 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 3 8.93 9.24

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL221007 DIASTEREOMER 2 1 9.24
CHEMBL518461 1 8.96
CHEMBL383484 1 8.59

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL221007 DIASTEREOMER 2 Ki = 0.57 nM 9.24
CHEMBL518461 Ki = 1.1 nM 8.96
CHEMBL383484 Ki = 2.6 nM 8.59