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Assay Detail

CHEMBL981149

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of CD45
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Intermediate

Target

Receptor-type tyrosine-protein phosphatase C (CHEMBL3243)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Illudalic acid as a potential LAR inhibitor: synthesis, SAR, and preliminary studies on the mechanism of action.
Ling Q, Huang Y, Zhou Y, Cai Z, Xiong B, Zhang Y, Ma L, Wang X, Li X, Li J, Shen J.
Bioorg Med Chem (2008) 16 : 7399 -7409
PubMed 18579388 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.55 6.55

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL515797 1 6.55

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL515797 IC50 = 280.0 nM 6.55