Assay Detail
Binding
CHEMBL981159
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Inhibition of IMP dehydrogenase
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Bis(sulfonamide) isosters of mycophenolic adenine dinucleotide analogues: inhibition of inosine monophosphate dehydrogenase.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 7.13 | 7.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL451855 | — | — | 1 | 7.40 |
| CHEMBL108358 | TIAZOFURIN | 2.0 | 1 | 7.00 |
| CHEMBL394276 | TIAZOFURIN ADENINE DINUCLEOTIDE | — | 1 | 7.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL451855 | — | Ki | = | 40.0 | nM | 7.40 |
| CHEMBL108358 | TIAZOFURIN | Ki | = | 100.0 | nM | 7.00 |
| CHEMBL394276 | TIAZOFURIN ADENINE DINUCLEOTIDE | Ki | = | 100.0 | nM | 7.00 |