Assay Detail
Functional
CHEMBL981215
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Antiviral activity against Poliovirus type 1 Lsc-2ab in human FL cells
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Poliovirus 1 |
| Cell Type | FL |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Cinnamoyl- and hydroxycinnamoyl amides of glaucine and their antioxidative and antiviral activities.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.28 | 5.92 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL470881 | OXOGLAUCINE | — | 1 | 5.92 |
| CHEMBL283639 | DISOXARIL | 2.0 | 1 | 5.70 |
| CHEMBL228082 | GLAUCINE | — | 1 | 4.22 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL470881 | OXOGLAUCINE | IC50 | = | 1200.0 | nM | 5.92 |
| CHEMBL283639 | DISOXARIL | IC50 | = | 2000.0 | nM | 5.70 |
| CHEMBL228082 | GLAUCINE | IC50 | = | 60000.0 | nM | 4.22 |