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Assay Detail

CHEMBL982123

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to dopamine D3 receptor
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Intermediate

Target

D(3) dopamine receptor (CHEMBL234)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

[11C]cyclopropyl-FLB 457: a PET radioligand for low densities of dopamine D2 receptors.
Airaksinen AJ, Nag S, Finnema SJ, Mukherjee J, Chattopadhyay S, Gulyás B, Farde L, Halldin C.
Bioorg Med Chem (2008) 16 : 6467 -6473
PubMed 18534857 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 9.66 9.66

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL289330 1 9.66

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL289330 Ki = 0.22 nM 9.66