Assay Detail
Binding
CHEMBL982801
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human purine nucleoside phosphorylase by xanthine-oxidase coupled assay
4
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
A beta-fluoroamine inhibitor of purine nucleoside phosphorylase.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 10.09 | 10.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL269864 | ULODESINE | 2.0 | 1 | 10.96 |
| CHEMBL498940 | — | — | 2 | 10.49 |
| CHEMBL522870 | — | — | 1 | 8.74 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL269864 | ULODESINE | Ki | = | 0.011 | nM | 10.96 |
| CHEMBL498940 | — | Ki | = | 0.032 | nM | 10.49 |
| CHEMBL498940 | — | Ki | = | 0.066 | nM | 10.18 |
| CHEMBL522870 | — | Ki | = | 1.82 | nM | 8.74 |