Assay Detail

CHEMBL982884

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ADMET

Cytotoxicity against african green monkey Vero cells after 48 hrs by neutral red assay

ChEMBL ↗

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Target

Vero (CHEMBL391) ↗

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Primary target Vero

CHEMBL391

Anchored from Assay target.

Protein identity Vero

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	ADMET
Organism	Chlorocebus sabaeus
Cell Type	Vero
Confidence	1 — Organism
Curated By	Autocuration

Target

Vero (CHEMBL391) ↗

Type	CELL-LINE
Organism	Chlorocebus sabaeus

Publication

2-N-Methyl modifications and SAR studies of manzamine A.

Ibrahim MA, Shilabin AG, Prasanna S, Jacob M, Khan SI, Doerksen RJ, Hamann MT.
Bioorg Med Chem (2008) 16 : 6702 -6706
PubMed 18595720 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	6.30	6.30

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL403233	MANZAMINE A	—	1	6.30

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL403233	MANZAMINE A	IC50	=	501.0	nM	6.30