Assay Detail
ADMET
CHEMBL983177
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Cytotoxicity against human H9 cells
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Cell Type | H9 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
New pyranocoumarins isolated from Calophyllum lanigerum and Calophyllum teysmannii.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 5.32 | 6.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL462675 | — | — | 1 | 6.00 |
| CHEMBL92735 | CALANOLIDE E2 | — | 1 | 5.60 |
| CHEMBL507953 | PSEUDOCARDATOLIDE C | — | 1 | 5.58 |
| CHEMBL7187 | COSTATOLIDE | — | 1 | 5.01 |
| CHEMBL518356 | CALANOLIDE F | — | 1 | 4.90 |
| CHEMBL462029 | CORDATOLIDE E | — | 1 | 4.85 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL462675 | — | IC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL92735 | CALANOLIDE E2 | IC50 | = | 2500.0 | nM | 5.60 |
| CHEMBL507953 | PSEUDOCARDATOLIDE C | IC50 | = | 2600.0 | nM | 5.58 |
| CHEMBL7187 | COSTATOLIDE | IC50 | = | 9800.0 | nM | 5.01 |
| CHEMBL518356 | CALANOLIDE F | IC50 | = | 12700.0 | nM | 4.90 |
| CHEMBL462029 | CORDATOLIDE E | IC50 | = | 14000.0 | nM | 4.85 |