Assay Detail
Functional
CHEMBL983827
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of LPS-stimulated TNF alpha release in human PBMC cells by ELISA
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | PBMC |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Biphenyl amide p38 kinase inhibitors 3: Improvement of cellular and in vivo activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.60 | 5.60 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL273158 | — | — | 1 | 5.60 |
| CHEMBL478649 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL273158 | — | IC50 | = | 2500.0 | nM | 5.60 |
| CHEMBL478649 | — | IC50 | = | 250000.0 | nM | - |