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Assay Detail

CHEMBL984058

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of Escherichia coli RNase H
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Escherichia coli
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Specific inhibition of human immunodeficiency virus type 1 reverse transcriptase mediated by soulattrolide, a coumarin isolated from the latex of calophyllum teysmannii.
Pengsuparp T, Serit M, Hughes SH, Soejarto DD, Pezzuto JM.
J Nat Prod (1996) 59 : 839 -842
PubMed 8864237 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.16 4.16

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL466773 SOULATTROLIDE 1 4.16

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL466773 SOULATTROLIDE IC50 = 69500.0 nM 4.16