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Assay Detail

CHEMBL984176

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Binding
Inhibition of ECK
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Intermediate

Target

Ephrin type-A receptor 2 (CHEMBL2068)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Discovery and characterization of the N-phenyl-N'-naphthylurea class of p38 kinase inhibitors.
Cirillo PF, Hickey ER, Moss N, Breitfelder S, Betageri R, Fadra T, Gaenzler F, Gilmore T, Goldberg DR, Kamhi V, Kirrane T, Kroe RR, Madwed J, Moriak M, Netherton M, Pargellis CA, Patel UR, Qian KC, Sharma R, Sun S, Swinamer A, Torcellini C, Takahashi H, Tsang M, Xiong Z.
Bioorg Med Chem Lett (2009) 19 : 2386 -2391
PubMed 19356929 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.28 5.28

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL451523 1 5.28

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL451523 IC50 = 5200.0 nM 5.28