Assay Detail
Functional
CHEMBL984431
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Antiviral activity against HSV1 infected in Vero76 cells assessed as reduction in virus plaque formation after 4 days by MTT assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Human alphaherpesvirus 1 |
| Cell Type | Vero 76 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Antimicrobial and cytotoxic arylazoenamines. Part III: antiviral activity of selected classes of arylazoenamines.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 4 | 4.43 | 4.60 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL448063 | — | — | 1 | 4.60 |
| CHEMBL478860 | — | — | 1 | 4.48 |
| CHEMBL446474 | — | — | 1 | 4.40 |
| CHEMBL518286 | — | — | 1 | 4.22 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL448063 | — | EC50 | = | 25000.0 | nM | 4.60 |
| CHEMBL478860 | — | EC50 | = | 33000.0 | nM | 4.48 |
| CHEMBL446474 | — | EC50 | = | 40000.0 | nM | 4.40 |
| CHEMBL518286 | — | EC50 | = | 60000.0 | nM | 4.22 |