Assay Detail
Binding
CHEMBL985098
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of COX2 in LPS-stimulated human whole blood assessed as TXB2 production by enzyme immunoassay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Tissue | Blood |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Novel 6-methanesulfonamide-3,4-methylenedioxyphenyl-N-acylhydrazones: orally effective anti-inflammatory drug candidates.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.23 | 5.46 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL56367 | NIMESULIDE | 4.0 | 1 | 5.46 |
| CHEMBL482199 | — | — | 1 | 4.99 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL56367 | NIMESULIDE | IC50 | = | 3500.0 | nM | 5.46 |
| CHEMBL482199 | — | IC50 | = | 10200.0 | nM | 4.99 |