Assay Detail
Binding
CHEMBL985910
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Binding affinity to biotinylated HIV1 trans-activation response element RNA by surface plasmon resonance analysis
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Human immunodeficiency virus 1 |
| Confidence | 3 — Cell-line / Tissue |
| Curated By | Autocuration |
Publication
Synthesis and evaluation of novel neamine derivatives effectively targeting to RNA.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 4 | 5.17 | 5.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL470645 | — | — | 1 | 5.70 |
| CHEMBL469608 | — | — | 1 | 5.52 |
| CHEMBL469394 | — | — | 1 | 4.85 |
| CHEMBL427409 | NEAMINE | — | 1 | 4.62 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL470645 | — | Kd | = | 2000.0 | nM | 5.70 |
| CHEMBL469608 | — | Kd | = | 3000.0 | nM | 5.52 |
| CHEMBL469394 | — | Kd | = | 14000.0 | nM | 4.85 |
| CHEMBL427409 | NEAMINE | Kd | = | 24000.0 | nM | 4.62 |