Assay Detail
Binding
CHEMBL985943
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of GABA transaminase in rat brain by Kitz-Wilson plot
4
Total Activities
2
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Tissue | Brain |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
4-aminobutyrate aminotransferase, mitochondrial (CHEMBL3148) ↗| Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
Publication
Inactivation of GABA transaminase by 3-chloro-1-(4-hydroxyphenyl)propan-1-one.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.09 | 5.40 |
| Activity | 2 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL500579 | — | — | 3 | 5.40 |
| CHEMBL14193 | 4-HYDROXYBENZALDEHYDE | — | 1 | 4.78 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL500579 | — | IC50 | = | 3990.0 | nM | 5.40 |
| CHEMBL14193 | 4-HYDROXYBENZALDEHYDE | IC50 | = | 16500.0 | nM | 4.78 |
| CHEMBL500579 | — | Activity | - | — | - | |
| CHEMBL500579 | — | Activity | - | — | - |