Assay Detail
Binding
CHEMBL986942
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]raclopride from human cloned dopamine D2 receptor expressed in CHO cell membrane
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | CHO |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Synthesis and neuropharmacological characterization of 2-O-substituted apomorphines.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 7.66 | 8.42 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL517028 | — | — | 1 | 8.42 |
| CHEMBL53 | APOMORPHINE | 4.0 | 1 | 7.50 |
| CHEMBL465054 | — | — | 1 | 7.06 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL517028 | — | Ki | = | 3.8 | nM | 8.42 |
| CHEMBL53 | APOMORPHINE | Ki | = | 32.0 | nM | 7.50 |
| CHEMBL465054 | — | Ki | = | 88.0 | nM | 7.06 |