Assay Detail
Binding
CHEMBL987143
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Inhibition of CK1alpha
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Intermediate |
Publication
Identification of novel protein kinase CK1 delta (CK1delta) inhibitors through structure-based virtual screening.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.57 | 5.91 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL576349 | IC261 | — | 1 | 5.91 |
| CHEMBL86771 | — | — | 1 | 5.40 |
| CHEMBL88326 | — | — | 1 | 5.40 |
| CHEMBL17594 | QUINIZARIN | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL576349 | IC261 | IC50 | = | 1240.0 | nM | 5.91 |
| CHEMBL86771 | — | IC50 | = | 4000.0 | nM | 5.40 |
| CHEMBL88326 | — | IC50 | = | 4000.0 | nM | 5.40 |
| CHEMBL17594 | QUINIZARIN | IC50 | > | 40000.0 | nM | - |