Assay Detail
Functional
CHEMBL987424
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Cytotoxicity against human HEPG2 cells after 24 hrs by MTT assay
13
Total Activities
13
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HepG2 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Gallic acid-based indanone derivatives as anticancer agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 13 | 5.41 | 8.05 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL428647 | PACLITAXEL | 4.0 | 1 | 8.05 |
| CHEMBL479761 | — | — | 1 | 5.83 |
| CHEMBL61 | PODOFILOX | 4.0 | 1 | 5.32 |
| CHEMBL480509 | — | — | 1 | 5.05 |
| CHEMBL479950 | — | — | 1 | 4.13 |
| CHEMBL519428 | — | — | 1 | 4.05 |
| CHEMBL518306 | — | — | 1 | - |
| CHEMBL480139 | — | — | 1 | - |
| CHEMBL518159 | — | — | 1 | - |
| CHEMBL479949 | — | — | 1 | - |
| CHEMBL446818 | — | — | 1 | - |
| CHEMBL480508 | — | — | 1 | - |
| CHEMBL480320 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL428647 | PACLITAXEL | IC50 | = | 9.0 | nM | 8.05 |
| CHEMBL479761 | — | IC50 | = | 1490.0 | nM | 5.83 |
| CHEMBL61 | PODOFILOX | IC50 | = | 4800.0 | nM | 5.32 |
| CHEMBL480509 | — | IC50 | = | 9000.0 | nM | 5.05 |
| CHEMBL479950 | — | IC50 | = | 74600.0 | nM | 4.13 |
| CHEMBL519428 | — | IC50 | = | 89700.0 | nM | 4.05 |
| CHEMBL518306 | — | IC50 | = | 102500.0 | nM | - |
| CHEMBL480139 | — | IC50 | = | 124000.0 | nM | - |
| CHEMBL518159 | — | IC50 | >= | 250000.0 | nM | - |
| CHEMBL479949 | — | IC50 | = | 111700.0 | nM | - |
| CHEMBL446818 | — | IC50 | >= | 250000.0 | nM | - |
| CHEMBL480508 | — | IC50 | >= | 250000.0 | nM | - |
| CHEMBL480320 | — | IC50 | = | 188000.0 | nM | - |