Assay Detail
Functional
CHEMBL987743
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Cytotoxicity against human A549 cells after 24 hrs by YO-PRO-1 assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | A549 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Isolation, structure elucidation and cytotoxic evaluation of endiandrin B from the Australian rainforest plant Endiandra anthropophagorum.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.13 | 5.13 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL375927 | (-)-DIHYDROGUAIARETICACID | — | 1 | 5.13 |
| CHEMBL107 | COLCHICINE | 4.0 | 1 | - |
| CHEMBL428647 | PACLITAXEL | 4.0 | 1 | - |
| CHEMBL388978 | STAUROSPORINE | — | 1 | - |
| CHEMBL428496 | WORTMANNIN | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL375927 | (-)-DIHYDROGUAIARETICACID | IC50 | = | 7490.0 | nM | 5.13 |
| CHEMBL107 | COLCHICINE | IC50 | = | 0.01078 | ug.mL-1 | - |
| CHEMBL428647 | PACLITAXEL | IC50 | = | 0.01964 | ug.mL-1 | - |
| CHEMBL388978 | STAUROSPORINE | IC50 | = | 0.1399 | ug.mL-1 | - |
| CHEMBL428496 | WORTMANNIN | IC50 | = | 0.00428 | ug.mL-1 | - |