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Assay Detail

CHEMBL987746

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Induction of early stage apoptosis in human A549 cells assessed as mitotracker dye uptake
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type A549
Confidence 1 — Organism
Curated By Autocuration

Target

A549 (CHEMBL392)
Type CELL-LINE
Organism Homo sapiens

Publication

Isolation, structure elucidation and cytotoxic evaluation of endiandrin B from the Australian rainforest plant Endiandra anthropophagorum.
Davis RA, Barnes EC, Longden J, Avery VM, Healy PC.
Bioorg Med Chem (2009) 17 : 1387 -1392
PubMed 19138858 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.51 4.51

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL375927 (-)-DIHYDROGUAIARETICACID 1 4.51

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL375927 (-)-DIHYDROGUAIARETICACID IC50 = 31200.0 nM 4.51