Assay Detail
Binding
CHEMBL987970
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Inhibition of human aromatase by fluorometric assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Screening of herbal constituents for aromatase inhibitory activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.49 | 6.47 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL252642 | LIQUIRTIGENIN | — | 1 | 6.47 |
| CHEMBL157101 | KETOCONAZOLE | 4.0 | 1 | 5.52 |
| CHEMBL164 | MYRICETIN | — | 1 | 5.00 |
| CHEMBL253570 | GOSSYPETIN | — | 1 | 4.96 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL252642 | LIQUIRTIGENIN | IC50 | = | 340.0 | nM | 6.47 |
| CHEMBL157101 | KETOCONAZOLE | IC50 | = | 3000.0 | nM | 5.52 |
| CHEMBL164 | MYRICETIN | IC50 | = | 10000.0 | nM | 5.00 |
| CHEMBL253570 | GOSSYPETIN | IC50 | = | 11000.0 | nM | 4.96 |