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Assay Detail

CHEMBL987991

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against human PC-3 cells assessed as reduction of cell growth by SRB method
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type PC-3
Confidence 1 — Organism
Curated By Autocuration

Target

PC-3 (CHEMBL390)
Type CELL-LINE
Organism Homo sapiens

Publication

Synthesis of unsymmetrical biphenyls as potent cytotoxic agents.
Wu G, Guo HF, Gao K, Liu YN, Bastow KF, Morris-Natschke SL, Lee KH, Xie L.
Bioorg Med Chem Lett (2008) 18 : 5272 -5276
PubMed 18782668 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.54 6.54

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL475942 1 6.54

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL475942 IC50 = 290.0 nM 6.54