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Assay Detail

CHEMBL988089

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity at GPR109a
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Intermediate

Target

Hydroxycarboxylic acid receptor 2 (CHEMBL3785)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Nicotinic acid receptor agonists.
Boatman PD, Richman JG, Semple G.
J Med Chem (2008) 51 : 7653 -7662
PubMed 18983141 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 3 6.47 7.14

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL247921 1 7.14
CHEMBL128604 1 6.81
CHEMBL338405 1 5.46

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL247921 Ki = 72.0 nM 7.14
CHEMBL128604 Ki = 156.0 nM 6.81
CHEMBL338405 Ki = 3500.0 nM 5.46