Assay Detail
Binding
CHEMBL988375
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Displacement of [3H]LSD from human cloned 5HT6 receptor
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Synthesis and structure-activity relationship of 1H-indole-3-carboxylic acid pyridine-3-ylamides: a novel series of 5-HT2C receptor antagonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 6.18 | 6.18 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL14460 | SB-243213 | — | 1 | 6.18 |
| CHEMBL516452 | — | — | 1 | - |
| CHEMBL479952 | — | — | 1 | - |
| CHEMBL519103 | — | — | 1 | - |
| CHEMBL480699 | — | — | 1 | - |
| CHEMBL480127 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL14460 | SB-243213 | IC50 | = | 667.0 | nM | 6.18 |
| CHEMBL516452 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL479952 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL519103 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL480699 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL480127 | — | IC50 | > | 10000.0 | nM | - |