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Assay Detail

CHEMBL988960

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to human FRK
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Tyrosine-protein kinase FRK (CHEMBL4223)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Assessment of chemical coverage of kinome space and its implications for kinase drug discovery.
Bamborough P, Drewry D, Harper G, Smith GK, Schneider K.
J Med Chem (2008) 51 : 7898 -7914
PubMed 19035792 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 2 7.57 8.22

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL450519 1 8.22
CHEMBL515466 1 6.91

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL450519 Kd = 6.0 nM 8.22
CHEMBL515466 Kd = 122.0 nM 6.91