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Assay Detail

CHEMBL989313

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of pig kidney aldehyde reductase by spectrophotometry
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Sus scrofa
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Effect of Polygonum hydropiper sulfated flavonoids on lens aldose reductase and related enzymes.
Haraguchi H, Ohmi I, Sakai S, Fukuda A, Toihara Y, Fujimoto T, Okamura N, Yagi A.
J Nat Prod (1996) 59 : 443 -445
PubMed 8699190 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 9 4.30 4.36

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL457815 1 4.36
CHEMBL463755 1 4.30
CHEMBL463753 1 4.25
CHEMBL50 QUERCETIN 3.0 1 -
CHEMBL379064 ISORHAMNETIN 1 -
CHEMBL471479 PERSICARIN 1 -
CHEMBL457148 RHAMNAZIN 1 -
CHEMBL250450 ISOQUERCETIN 2.0 1 -
CHEMBL458251 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL457815 IC50 = 43500.0 nM 4.36
CHEMBL463755 IC50 = 49500.0 nM 4.30
CHEMBL463753 IC50 = 55600.0 nM 4.25
CHEMBL50 QUERCETIN IC50 > 91000.0 nM -
CHEMBL379064 ISORHAMNETIN IC50 > 95000.0 nM -
CHEMBL471479 PERSICARIN IC50 > 69000.0 nM -
CHEMBL457148 RHAMNAZIN IC50 > 91000.0 nM -
CHEMBL250450 ISOQUERCETIN IC50 > 64000.0 nM -
CHEMBL458251 IC50 > 50000.0 nM -