Assay Detail
Functional
CHEMBL989467
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Cytotoxicity against human NCI-H460 cells after 48 hrs by MTT assay
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | NCI-H460 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Cytotoxic constituents of Aspergillus terreus from the rhizosphere of Opuntia versicolor of the Sonoran Desert.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 10 | 5.08 | 8.02 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL428647 | PACLITAXEL | 4.0 | 1 | 8.02 |
| CHEMBL518807 | — | — | 1 | 5.03 |
| CHEMBL469079 | — | — | 1 | 4.97 |
| CHEMBL509106 | QUADRONE | — | 1 | 4.91 |
| CHEMBL467404 | — | — | 1 | 4.84 |
| CHEMBL467403 | ASTERREDIONE | — | 1 | 4.76 |
| CHEMBL511399 | — | — | 1 | 4.71 |
| CHEMBL512621 | ASTERRIQUINONE D | — | 1 | 4.70 |
| CHEMBL467829 | — | — | 1 | 4.62 |
| CHEMBL467203 | BETULINAN A | — | 1 | 4.23 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL428647 | PACLITAXEL | IC50 | = | 9.5 | nM | 8.02 |
| CHEMBL518807 | — | IC50 | = | 9400.0 | nM | 5.03 |
| CHEMBL469079 | — | IC50 | = | 10600.0 | nM | 4.97 |
| CHEMBL509106 | QUADRONE | IC50 | = | 12400.0 | nM | 4.91 |
| CHEMBL467404 | — | IC50 | = | 14500.0 | nM | 4.84 |
| CHEMBL467403 | ASTERREDIONE | IC50 | = | 17400.0 | nM | 4.76 |
| CHEMBL511399 | — | IC50 | = | 19400.0 | nM | 4.71 |
| CHEMBL512621 | ASTERRIQUINONE D | IC50 | = | 19900.0 | nM | 4.70 |
| CHEMBL467829 | — | IC50 | = | 24200.0 | nM | 4.62 |
| CHEMBL467203 | BETULINAN A | IC50 | = | 58400.0 | nM | 4.23 |