Assay Detail
Functional
CHEMBL989724
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Agonist activity at CB1 receptor
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Confidence | 8 — Homologous single protein target |
| Curated By | Intermediate |
Publication
Synthesis and cannabinoid activity of 1-substituted-indole-3-oxadiazole derivatives: novel agonists for the CB1 receptor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 8.18 | 9.49 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL28045 | — | — | 1 | 9.49 |
| CHEMBL188 | WIN-552122 | — | 1 | 8.70 |
| CHEMBL13178 | PRAVADOLINE | 2.0 | 1 | 6.34 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL28045 | — | IC50 | = | 0.32 | nM | 9.49 |
| CHEMBL188 | WIN-552122 | IC50 | = | 2.0 | nM | 8.70 |
| CHEMBL13178 | PRAVADOLINE | IC50 | = | 453.0 | nM | 6.34 |