Assay Detail
Binding
CHEMBL989797
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human sPLA2 group 2A
11
Total Activities
11
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Phospholipase A2, membrane associated (CHEMBL3474) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Simplified YM-26734 inhibitors of secreted phospholipase A2 group IIA.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 11 | 6.35 | 7.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL444450 | — | — | 1 | 7.10 |
| CHEMBL485601 | — | — | 1 | 6.16 |
| CHEMBL470757 | DIDODECANOYLPHLOROGLUCINOL | — | 1 | 5.80 |
| CHEMBL508033 | — | — | 1 | - |
| CHEMBL483770 | — | — | 1 | - |
| CHEMBL485443 | — | — | 1 | - |
| CHEMBL520514 | — | — | 1 | - |
| CHEMBL455273 | — | — | 1 | - |
| CHEMBL484180 | — | — | 1 | - |
| CHEMBL483761 | — | — | 1 | - |
| CHEMBL485614 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL444450 | — | IC50 | = | 80.0 | nM | 7.10 |
| CHEMBL485601 | — | IC50 | = | 690.0 | nM | 6.16 |
| CHEMBL470757 | DIDODECANOYLPHLOROGLUCINOL | IC50 | = | 1600.0 | nM | 5.80 |
| CHEMBL508033 | — | IC50 | > | 3300.0 | nM | - |
| CHEMBL483770 | — | IC50 | > | 1600.0 | nM | - |
| CHEMBL485443 | — | IC50 | > | 1600.0 | nM | - |
| CHEMBL520514 | — | IC50 | > | 1600.0 | nM | - |
| CHEMBL455273 | — | IC50 | > | 1600.0 | nM | - |
| CHEMBL484180 | — | IC50 | > | 1600.0 | nM | - |
| CHEMBL483761 | — | IC50 | > | 1600.0 | nM | - |
| CHEMBL485614 | — | IC50 | > | 1600.0 | nM | - |