Assay Detail
Binding
CHEMBL989800
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Inhibition of rabbit sPLA2 group 2A
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Oryctolagus cuniculus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Phospholipase A2, membrane associated (CHEMBL5481) ↗| Type | SINGLE PROTEIN |
| Organism | Oryctolagus cuniculus |
Publication
Simplified YM-26734 inhibitors of secreted phospholipase A2 group IIA.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.54 | 8.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL470757 | DIDODECANOYLPHLOROGLUCINOL | — | 1 | 8.00 |
| CHEMBL444450 | — | — | 1 | 7.07 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL470757 | DIDODECANOYLPHLOROGLUCINOL | IC50 | = | 10.0 | nM | 8.00 |
| CHEMBL444450 | — | IC50 | = | 85.0 | nM | 7.07 |