Assay Detail
Binding
CHEMBL989873
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Activity of verapamil-dependent ATPase in lipid activated mouse P-glycoprotein mdr3 cys-less mutant
2
Total Activities
1
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mus musculus |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Chalcogenopyrylium dyes as inhibitors/modulators of P-glycoprotein in multidrug-resistant cells.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Km | 1 | - | - |
| Ki | 1 | 7.40 | 7.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL457023 | — | — | 2 | 7.40 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL457023 | — | Ki | = | 40.0 | nM | 7.40 |
| CHEMBL457023 | — | Km | = | 16000.0 | nM | - |