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Assay Detail

CHEMBL990235

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of HIV1 recombinant gp120/CD4 interaction by ELISA
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

The complestatins as HIV-1 integrase inhibitors. Efficient isolation, structure elucidation, and inhibitory activities of isocomplestatin, chloropeptin I, new complestatins, A and B, and acid-hydrolysis products of chloropeptin I.
Singh SB, Jayasuriya H, Salituro GM, Zink DL, Shafiee A, Heimbuch B, Silverman KC, Lingham RB, Genilloud O, Teran A, Vilella D, Felock P, Hazuda D.
J Nat Prod (2001) 64 : 874 -882
PubMed 11473415 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.70 5.70

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL506605 ISOCOMPLESTATIN 1 5.70

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL506605 ISOCOMPLESTATIN IC50 = 2000.0 nM 5.70