Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL990719

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type HeLa
Confidence 1 — Organism
Curated By Autocuration

Target

HeLa (CHEMBL399)
Type CELL-LINE
Organism Homo sapiens

Publication

The design, synthesis, and anti-tumor mechanism study of N-phosphoryl amino acid modified resveratrol analogues.
Liu H, Dong A, Gao C, Tan C, Liu H, Zu X, Jiang Y.
Bioorg Med Chem (2008) 16 : 10013 -10021
PubMed 18952444 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 4 5.12 5.25

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL459547 1 5.25
CHEMBL457224 1 5.19
CHEMBL460619 1 5.02
CHEMBL458300 1 5.01

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL459547 IC50 = 5620.0 nM 5.25
CHEMBL457224 IC50 = 6410.0 nM 5.19
CHEMBL460619 IC50 = 9530.0 nM 5.02
CHEMBL458300 IC50 = 9750.0 nM 5.01