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Assay Detail

CHEMBL991270

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity agaisnt human MDA-MB-231 cells by SRB assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type MDA-MB-231
Confidence 1 — Organism
Curated By Autocuration

Target

MDA-MB-231 (CHEMBL400)
Type CELL-LINE
Organism Homo sapiens

Publication

Synthesis and biological activity of novel shikonin analogues.
Wang W, Dai M, Zhu C, Zhang J, Lin L, Ding J, Duan W.
Bioorg Med Chem Lett (2009) 19 : 735 -737
PubMed 19111464 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 5.34 5.35

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL481820 1 5.35
CHEMBL481999 1 5.33

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL481820 IC50 = 4500.0 nM 5.35
CHEMBL481999 IC50 = 4700.0 nM 5.33