Assay Detail
Binding
CHEMBL991387
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]5HT from 5HT1B receptor expressed in CHO cells
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Cell Type | CHO |
| Confidence | 8 — Homologous single protein target |
| Curated By | Intermediate |
Publication
The discovery of a selective, small molecule agonist for the MAS-related gene X1 receptor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 6.21 | 6.28 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL458001 | — | — | 1 | 6.28 |
| CHEMBL458220 | — | — | 1 | 6.23 |
| CHEMBL458002 | — | — | 1 | 6.11 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL458001 | — | Ki | = | 524.81 | nM | 6.28 |
| CHEMBL458220 | — | Ki | = | 588.84 | nM | 6.23 |
| CHEMBL458002 | — | Ki | = | 776.25 | nM | 6.11 |