Assay Detail
Binding
CHEMBL991392
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]LSD from 5HT6 receptor expressed in human HeLa cells
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Cell Type | HeLa |
| Confidence | 8 — Homologous single protein target |
| Curated By | Intermediate |
Publication
The discovery of a selective, small molecule agonist for the MAS-related gene X1 receptor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 5.95 | 6.31 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL458001 | — | — | 1 | 6.31 |
| CHEMBL458002 | — | — | 1 | 6.08 |
| CHEMBL458220 | — | — | 1 | 5.47 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL458001 | — | Ki | = | 489.78 | nM | 6.31 |
| CHEMBL458002 | — | Ki | = | 831.76 | nM | 6.08 |
| CHEMBL458220 | — | Ki | = | 3388.44 | nM | 5.47 |