Assay Detail
Binding
CHEMBL991725
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Inhibition of xanthine oxidase assessed as decrease of superoxide generation
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Intermediate |
Publication
ortho-dihydroxyisoflavone derivatives from aged Doenjang (Korean fermented soypaste) and its radical scavenging activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 4.87 | 5.18 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL242739 | — | — | 1 | 5.18 |
| CHEMBL13486 | — | — | 1 | 4.78 |
| CHEMBL1467 | ALLOPURINOL | 4.0 | 1 | 4.66 |
| CHEMBL239156 | — | — | 1 | - |
| CHEMBL8145 | DAIDZEIN | 2.0 | 1 | - |
| CHEMBL513024 | GLYCITEIN | — | 1 | - |
| CHEMBL44 | GENISTEIN | 2.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL242739 | — | IC50 | = | 6600.0 | nM | 5.18 |
| CHEMBL13486 | — | IC50 | = | 16800.0 | nM | 4.78 |
| CHEMBL1467 | ALLOPURINOL | IC50 | = | 21800.0 | nM | 4.66 |
| CHEMBL239156 | — | IC50 | > | 1000000.0 | nM | - |
| CHEMBL8145 | DAIDZEIN | IC50 | = | 429800.0 | nM | - |
| CHEMBL513024 | GLYCITEIN | IC50 | = | 682600.0 | nM | - |
| CHEMBL44 | GENISTEIN | IC50 | = | 232500.0 | nM | - |