Assay Detail
Binding
CHEMBL992719
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Inhibition of human DNA polymerase beta using D21/D36 DNA as a template
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Activity against human immunodeficiency virus type 1, intracellular metabolism, and effects on human DNA polymerases of 4'-ethynyl-2-fluoro-2'-deoxyadenosine.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.52 | 5.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1383 | DDA-TRIPHOSPHATE | -1.0 | 1 | 5.52 |
| CHEMBL518606 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1383 | DDA-TRIPHOSPHATE | IC50 | = | 3000.0 | nM | 5.52 |
| CHEMBL518606 | — | IC50 | > | 100000.0 | nM | - |