Assay Detail
Binding
CHEMBL993389
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]ketanserin from 5HT2A receptor expressed in cells
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Intermediate |
Publication
Synthesis of 6-substituted 1-phenylbenzazepines and their dopamine D(1) receptor activities.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 6 | 6.91 | 7.37 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL520821 | — | — | 1 | 7.37 |
| CHEMBL484538 | — | — | 1 | 6.92 |
| CHEMBL485207 | — | — | 1 | 6.43 |
| CHEMBL484352 | — | — | 1 | - |
| CHEMBL485036 | — | — | 1 | - |
| CHEMBL485041 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL520821 | — | Ki | = | 43.0 | nM | 7.37 |
| CHEMBL484538 | — | Ki | = | 121.0 | nM | 6.92 |
| CHEMBL485207 | — | Ki | = | 375.0 | nM | 6.43 |
| CHEMBL484352 | — | Ki | - | — | - | |
| CHEMBL485036 | — | Ki | - | — | - | |
| CHEMBL485041 | — | Ki | - | — | - |