Assay Detail
Binding
CHEMBL993555
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of starfish cdc2/cyclin B assessed as [32P] incorporation in histone H1 from 150 M [gamma32P]ATP
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Patiria pectinifera |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Exploiting chemical libraries, structure, and genomics in the search for kinase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.35 | 7.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL23327 | PURVALANOLA | — | 1 | 7.40 |
| CHEMBL23254 | PURVALANOL B | — | 1 | 7.30 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL23327 | PURVALANOLA | IC50 | = | 40.0 | nM | 7.40 |
| CHEMBL23254 | PURVALANOL B | IC50 | = | 50.0 | nM | 7.30 |