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Assay Detail

CHEMBL993559

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to CB1 receptor
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Intermediate

Target

Cannabinoid receptor 1 (CHEMBL218)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Comparative molecular dynamics simulations of the potent synthetic classical cannabinoid ligand AMG3 in solution and at binding site of the CB1 and CB2 receptors.
Durdagi S, Reis H, Papadopoulos MG, Mavromoustakos T.
Bioorg Med Chem (2008) 16 : 7377 -7387
PubMed 18595717 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 9.49 9.49

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL476325 1 9.49

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL476325 Ki = 0.32 nM 9.49