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Assay Detail

CHEMBL993920

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to 5HT3 receptor
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

5-hydroxytryptamine receptor 3A (CHEMBL1899)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

New N-substituted 9-azabicyclo[3.3.1]nonan-3alpha-yl phenylcarbamate analogs as sigma2 receptor ligands: synthesis, in vitro characterization, and evaluation as PET imaging and chemosensitization agents.
Chu W, Xu J, Zhou D, Zhang F, Jones LA, Wheeler KT, Mach RH.
Bioorg Med Chem (2009) 17 : 1222 -1231
PubMed 19119012 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 2 9.00 9.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL62023 1 9.00
CHEMBL481425 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL62023 Ki = 1.0 nM 9.00
CHEMBL481425 Ki > 1000.0 nM -